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Search Results for " ddr1/2 inhibitor-2 "

8

Compounds

Cat No. Product Name Synonyms Targets
T79811 DDR1/2 inhibitor-2
DDR1/2 Inhibitor-2 (Example 31) serves as an inhibitor of DDR1/DDR2, exhibiting IC50 values below 100 nM. It is applicable in cancer and fibrotic disease research [1].
T5402 DDR1-IN-2 DDR1 inhibitor 7rh Discoidin Domain Receptor (DDR)
DDR1-IN-2 (DDR1 inhibitor 7rh) (DDR1 inhibitor 7rh) is a potent, selective, ATP-competitive Discoidin domain receptor 1 (DDR1) inhibitor (IC50: 6.8 nM in cell-free kinase assays).
T4646 TA-02 p38 MAPK , Autophagy
TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.
T70201 S 16020-2
S 16020-2 is an olivacine derivative, and DNA topoisomerase II inhibitor endowed with a remarkable antitumor activity against various experimental tumors.
T7862 VU6015929 Discoidin Domain Receptor (DDR)
VU6015929 is an inhibitor of active dual discoidin domain receptor 1/2 (DDR1/2)( IC50s of 4.67 nM and 7.39 nM, respectively).
T60805 JNK3 inhibitor-2
JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor. The IC50 values of JNK3 inhibitor-2 for JNK1, JNK2, JNK3 are >100, >100, 0.25 μM, respectively. JNK3 inhibitor-2 also inhibits DDR1 and EGFR (T790M, L858R) [1].
T12925 Sitravatinib malate MGCD516 malate,MG-516 malate TAM Receptor
Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT...
T15808 Merestinib dihydrochloride LY2801653 dihydrochloride ROCK
Merestinib dihydrochloride is an effective and orally bioavailable c-Met inhibitor (Ki=2 nM). It has anti-tumor activities and also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK...
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